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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXK
All Species:
24.55
Human Site:
S423
Identified Species:
60
UniProt:
P42681
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42681
NP_003319.2
527
61258
S423
L
D
D
E
Y
V
S
S
F
G
A
K
F
P
I
Chimpanzee
Pan troglodytes
XP_517311
461
53260
F358
D
D
E
Y
V
S
S
F
G
A
K
F
P
I
K
Rhesus Macaque
Macaca mulatta
XP_001103052
527
61170
S423
L
D
D
E
Y
V
S
S
F
G
A
K
F
P
I
Dog
Lupus familis
XP_539258
585
67628
S459
L
D
D
E
Y
I
S
S
S
G
A
K
F
P
I
Cat
Felis silvestris
Mouse
Mus musculus
P42682
527
61090
S423
L
D
D
E
Y
I
S
S
S
G
A
K
F
P
V
Rat
Rattus norvegicus
Q07014
512
58642
W409
G
A
K
F
P
I
K
W
T
A
P
E
A
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515402
583
67167
S476
L
D
D
Q
Y
T
S
S
S
G
A
K
F
P
V
Chicken
Gallus gallus
Q8JH64
657
75860
S552
L
D
D
E
Y
T
S
S
M
G
S
K
F
P
V
Frog
Xenopus laevis
P13116
532
59718
R418
E
D
N
E
Y
T
A
R
Q
G
A
K
F
P
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08630
786
87374
S680
L
D
D
Q
Y
T
S
S
G
G
T
K
F
P
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.7
96.9
78.9
N.A.
83.4
36.2
N.A.
51.1
45.2
36.6
N.A.
N.A.
33.7
N.A.
N.A.
N.A.
Protein Similarity:
100
87
98.2
84.4
N.A.
92.4
56.1
N.A.
67.2
59.2
52.6
N.A.
N.A.
45.9
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
86.6
N.A.
80
0
N.A.
73.3
73.3
60
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
100
93.3
N.A.
93.3
13.3
N.A.
86.6
86.6
73.3
N.A.
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
10
0
0
20
60
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
90
70
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
10
60
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
10
20
0
0
10
80
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
20
80
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
30
0
0
0
0
0
0
0
20
50
% I
% Lys:
0
0
10
0
0
0
10
0
0
0
10
80
0
0
10
% K
% Leu:
70
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
10
0
10
80
0
% P
% Gln:
0
0
0
20
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
80
70
30
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
40
0
0
10
0
10
0
0
0
0
% T
% Val:
0
0
0
0
10
20
0
0
0
0
0
0
0
0
30
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
80
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _